Evaluation of serotonin receptors (5HTR2A and 5HTR3A) mRNA expression changes in tumor of breast cancer patients
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولGene Expression Changes of Serotonin Receptors, 5-HT3AR and 5-HT2AR, in Breast Cancer Patients
Breast cancer is a serious and potentially lethal disease among 40-50 aged women and its incident rate is one out of eight in the United States and one out of thirty five people in Asia. Incidence of breast carcinoma is 10 per 100,000 of population with 7000 new cases annually in Iran. The age specific rate in females is 23.16/100,000. Every year 1200 women die due to breast carcinoma with burd...
متن کاملAlternative Viewpoint Against Breast Cancer Based on Selective Serotonin Receptors 5HTR3A and 5HTR2A Antagonists that can Mediate Apoptosis in MCF-7 Cell Line.
BACKGROUND Neurotransmitters had progressive effects on various cancers via their different type of receptors. OBJECTIVE This study was conducted to determine the pattern of serotonin receptors, respectively, 5HTR2A and 5HTR3A gene expression in MCF-7 cells and evaluate their selective antagonist effects on them. METHOD RT-PCR was performed to determine the pattern of serotonin receptor gen...
متن کاملMir-183 and FOXO1 gene expression changes in peripheral blood mononuclear cells of breast cancer patients
Background and Aim: Today, cancer is considered as a major health problem and affects the health of society. Breast cancer is the second leading cause of cancer death in women after lung cancer. According to epidemiological studies, cancer is the second most common cause of death after cardiovascular disease worldwide and the third leading cause of death after cardiovascular disease and acciden...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Journal of The Islamic Republic of Iran
سال: 2020
ISSN: 1016-1430,2251-6840
DOI: 10.47176/mjiri.34.99